What does LD50 stand for in toxicology?

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LD50 stands for "Lethal Dose 50% for a population," which refers to the amount of a substance required to kill 50% of a test population, typically within a specified timeframe. This measure is crucial in toxicology as it provides a standardized way to assess the toxicity of various substances, including pesticides. By understanding the LD50 value, researchers and applicators can gauge the relative potential danger of a chemical used in agriculture or pest control.

This concept is particularly significant in risk assessment and regulatory evaluations, allowing for comparisons between different chemicals based on their toxicity. A lower LD50 indicates a higher toxicity, meaning a smaller amount of the substance would be lethal to half the population being tested. This information is vital for ensuring safe handling practices and determining appropriate application methods to minimize risks to humans, wildlife, and the environment.

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