What signal word indicates pesticides with very high oral LD50 values?

The signal word "CAUTION" is used to indicate pesticides that have very high oral LD50 values, meaning they are relatively less toxic compared to those labeled with more alarming signal words. The LD50 (lethal dose for 50% of the test population) is a standard measure of acute toxicity, and a high LD50 value suggests that a comparatively larger amount of the pesticide would be required to cause harm.

In the context of pesticide labeling, the use of "CAUTION" denotes a lower level of toxicity, signaling to the user that the product poses minimal risk under normal handling and application conditions. This is particularly important for applicators, as it allows them to understand the relative risk and make informed decisions about how to handle and apply the pesticide safely, while also complying with legal requirements for clear labeling.

In contrast, "DANGER" and "WARNING" are used for products with lower LD50 values, indicating higher levels of toxicity and more significant risks to health. "SAFE," which is not a recognized signal word in this context, would not indicate any level of risk assessment and is therefore not applicable when discussing pesticide toxicity.