Which of the following is NOT a systemic effect of pesticide exposure?

A skin rash is not considered a systemic effect of pesticide exposure because it is typically a localized reaction that occurs on the skin due to direct contact with the chemical. Systemic effects, on the other hand, are those that involve the entire body and occur when a pesticide enters the bloodstream and affects organs and systems beyond the site of contact.

In contrast, cancers, reproductive issues, and hormonal effects are all systemic effects. These issues arise from the body's response to chemicals that have been absorbed systemically, often leading to long-term health concerns. For instance, certain pesticides can disrupt hormonal balance, contribute to reproductive challenges, or even increase the risk of developing cancers as they interfere with cellular processes throughout the body. Understanding these distinctions is crucial for recognizing the potential health impacts of pesticide exposure.