Which of the following measures is primarily used to assess the degree of acute toxicity?

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The measure primarily used to assess the degree of acute toxicity is LD50, which stands for "lethal dose for 50% of the population." This metric quantifies the amount of a substance that, when administered, kills half of a test population within a specified period. It is a critical measurement in toxicology that provides insight into the toxicity level of a chemical, allowing for the comparison of the toxicity of different substances.

LD50 is usually expressed in terms of milligrams of substance per kilogram of body weight (mg/kg), which enables researchers to evaluate the potential harm a substance may pose to humans, animals, or other organisms based on the dosage and effects observed during studies. This information is particularly important for regulatory purposes, safety assessments, and the informed use of pesticides.

Other options, while relevant in toxicology, serve different purposes. For example, LC50 measures the concentration of a substance in the air or water that is lethal to 50% of the test organisms over a specific time, making it more relevant for assessing toxicity in an environmental context, like aquatic or aerial exposure. NOAEL (No Observed Adverse Effect Level) relates to the highest dose at which no adverse effects are observed and is more concerned with chronic toxicity rather

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